![]() ![]() Most of these patterns tended to return to normal when symptoms resolved.Ĭonclusion: This review identified a paucity of controlled studies in the field of dissociative amnesia neuroimaging, which restricts the extrapolation of results. When trying to recollect memories from an amnestic period compared to a non-amnestic period, patients failed to activate these structures efficiently. When testing recognition of memories from the amnestic period, patients showed increased activation across temporal areas (hippocampal and para-hippocampal gyri) and the limbic network. The patients also presented abnormal patterns of cerebral activation when performing memory tasks. In resting state, neuroimaging studies mostly showed a hypo-activated right inferolateral prefrontal cortex, associated with limbic hypoactivity and lesser activation of the hippocampal and para-hippocampal structures. The other 21 were case reports and case series. Only one was a controlled study with a large sample. Results: Twenty-two studies met our inclusion criteria (gathering 49 patients). We included every scientific report involving patients undergoing a functional imaging procedure. Methods: We conducted a systematic review of the scientific literature available on PubMed, up to December 1, 2022, using a combination of keywords referring to dissociative amnesia. This condition remains poorly understood and this review aims to investigate the neuroanatomical feature of this disease. 4Pôle Neurosciences, CHU de Toulouse, Toulouse, FranceĪim: Dissociative amnesia is an emblematic psychiatric condition in which patients experience massive memory loss ranging from focal to global amnesia.3Service Universitaire de Psychiatrie et Psychologie Médicale, CHU de Toulouse, Toulouse, France.2Service de Psychiatrie, Psychothérapie et Art-Thérapie, Centre Expert du Stress Traumatique, CHU de Toulouse, Toulouse, France.1INSERM U1214 Centre d’Imagerie Neuro Toulouse (ToNIC), Toulouse, France.Simon Taïb 1,2* Antoine Yrondi 1,3 Béatrice Lemesle 4 Patrice Péran 1 Jérémie Pariente 1,4 ![]()
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